I stumbled across a post about this mutation and found it very interesting

Alexandria’s Genesis, a.k.a violet eyes (a genetic mutation).

    When someone is born with Alexandria’s Genesis, their eyes are blue or gray at birth. After six months, the eyes begin to change from their original color to purple, and this process lasts six months. During puberty, the color deepens to dark purple, a deep purple, a royal purple, or a violet-blue color and remains that way. It does not affect the person’s eyesight.

          Those who have this mutation will never grow any facial, body, pubic, or anal hair (not including hair on their head, on their ears, noses, eyebrows and eyelashes) Women also do not menstruate, but are fertile.

 Characteristics are:

• Clear, silver-like purple eyes (after 1^st birthday; deepen in color until onset of puberty)
• No facial or body hair growth beyond what was already there at birth
• Dark brown or black hair
• Shimmering white skin that resist tanning and burning
• Lack of menstruation cycle (in women)
• Highly evolved immune system (has been known to resist every disease known to man so far)
• Appear 5-20 years younger (after the age of 21, the aging process slows down greatly; it stops completely between the ages of 40-50)
• Long life span (ranges from 130-170 years)
• Perfect vision
• Never overweight (their metabolism prevents the gaining of too much fat [a.k.a., partial lipodystophy])
• Well-developed and proportioned bodies
• Found mainly in women of Euro-American descent
• Women are the primary carriers of the mutation
• Children born from mothers with the mutation are also carriers
• Mutation remains active generation after generation
• Mutation grows stronger generation after generation

    In ten percent of the population that has "Alexandria's Genesis," there is another characteristic of this mutation that is increasing on a yearly basis: the processing of human waste… or lack thereof.As it turns out, in some of these people, the mutation is actually causing the digestive system to produce no waste. No one has found out how this is possible, but most scientists have a theory that may explain this increasing phenomenon.
   The digestion process goes through its normal procedure until the digested product enters the large intestine. It is there, scientists suggest, that the large intestine absorbs everything and uses the product to keep the body in top shape. This makes the bladder completely useless, and leaves the small intestine and rectum as just an opening. It is not much of a theory, since very little is still known about "Alexandria's Genesis."

So basically it's the best genetic mutation/birth defect ever!  I see nothing wrong with it besides the whole non-aging thing. But other people may really like that factor.